Article
Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.
BMC medical genetics - 22 Mar 2005
Ghoussaini Maya, Meyre David, Lobbens Stéphane, Charpentier Guillaume, Clément Karine, Charles Marie-Aline, Tauber Maïté, Weill Jacques, Froguel Philippe
Abstract excerpt
BACKGROUND: The Pro12Ala Single Nucleotide Polymorphism (SNP) of the Peroxisome Proliferator-Activated Receptor gamma 2 (PPAR-gamma 2) has been associated with insulin resistance and type 2 diabetes (T2D) and also inconsistently with obesity. The aim of this study was to evaluate the impact of this SNP with regards to T2D and childhood and adult obesity in the French Caucasian population. METHODS: We conducted...
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