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Article

Wnt signaling and hepatocarcinogenesis: the hepatoblastoma model.

The international journal of biochemistry & cell biology - 1 Feb 2011

Armengol C, Cairo S, Fabre M, Buendia M A

Abstract excerpt

The Wnt/β-catenin pathway plays a key role in liver development, regeneration and tumorigenesis. Among human cancers tightly linked to abnormal Wnt/β-catenin signaling, hepatoblastoma (HB) presents with the highest rate (50-90%) of β-catenin mutations. HB is the most common malignant tumor of the liver in childhood. This embryonic tumor differs from hepatocellular carcinoma by the absence of viral etiology and...

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Identifiers

PMID: 19646548
DOI: 10.1016/j.biocel.2009.07.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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