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Article

Activation of Wnt and Myc signaling in hepatoblastoma.

Frontiers in bioscience (Elite edition) - 1 Jan 2012

Cairo Stefano, Armengol Carolina, Buendia Marie Annick

Abstract excerpt

Hepatoblastoma (HB) is the most common type of pediatric liver cancer. This tumor is thought to derive from hepatic progenitor cells that are arrested at various stages of liver development, as illustrated by a variety of histologic subtypes. Recent genomic studies have led to better understand the molecular pathogenesis of HB, to point out the crucial roles of the Wnt Myc signaling pathways in malignant...

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beta Catenin
Hepatoblastoma
Liver Neoplasms
Mutation
Proto-Oncogene Proteins c-myc
Signal Transduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Wnt/β-catenin signaling in development and cancer

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PMID: 22201888
DOI: 10.2741/e393

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