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Article

Lobular carcinoma in situ of the breast is not caused by constitutional mutations in the E-cadherin gene.

British journal of cancer - 1 Feb 2000

Rahman N, Stone J G, Coleman G, Gusterson B, Seal S, Marossy A, Lakhani S R, Ward A, Nash A, McKinna A, A'Hern R, Stratton M R, Houlston R S

Abstract excerpt

Lobular carcinoma in situ (LCIS) is an unusual histological pattern of non-invasive neoplastic disease of the breast occurring predominantly in women aged between 40 and 50 years. LCIS is frequently multicentric and bilateral, and there is evidence that it is associated with an elevated familial risk of breast cancer. Although women with LCIS suffer an increased risk of invasive breast disease, this risk is...

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Identifiers

PMID: 10682667
DOI: 10.1054/bjoc.1999.0965
PMCID: PMC2363330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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