Article
Biomarker profile and genetic abnormalities in lobular carcinoma in situ.
Breast cancer research and treatment - 1 Apr 2005
Mohsin Syed K, O'Connell Peter, Allred D Craig, Libby Arlene L
Abstract excerpt
The predisposition of patients with lobular carcinoma in situ (LCIS) to develop invasive breast cancer (IBC) is well known. However, relatively little is known about the biologic characteristics, which may be involved in the development and progression of LCIS. This study evaluated 59 cases of LCIS (29 pure, 30 with synchronous IBC) for five biomarkers known to be important in IBC (ER, PgR, c-erbB-2, p53 and...
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