Genetic basis of induction and overproduction of chromosomal class I beta-lactamase in nonfastidious gram-negative bacilli.

doi:10.1093/clinids/10.4.782

Back to search

Article

Genetic basis of induction and overproduction of chromosomal class I beta-lactamase in nonfastidious gram-negative bacilli.

Reviews of infectious diseases - 1 Jan 2000

Lindberg F, Lindquist S, Normark S

Abstract excerpt

Pseudomonas and several species of gram-negative enterobacteria produce low levels of chromosomally encoded class I beta-lactamase. The level of synthesis can be greatly increased by the addition of beta-lactam antibiotics into the growth medium. Moreover, mutants overproducing the enzyme arise a...

Topics

Chromosomes, Bacterial
Enterobacteriaceae
Enzyme Induction
Gram-Negative Bacteria
Mutation
Pseudomonas
beta-Lactamases

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.