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Article

An Unusual Form of Purifying Selection in a Sperm Protein

1 Feb 2000

Abstract excerpt

Protamines are small, highly basic DNA-binding proteins found in the sperm of animals. Interestingly, the proportion of arginine residues in one type of protamine, protamine P1, is about 50% in mammals. Upon closer examination, it was found that both the total number of amino acids and the positions of arginine residues have changed considerably during the course of mammalian evolution. This evolutionary pattern...

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PMID: 10677850
DOI: 10.1093/oxfordjournals.molbev.a026307

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