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Article

Rapid evolution of a primate sperm protein: relaxation of functional constraint or positive Darwinian selection?

1 May 1999

Abstract excerpt

Protamines are arginine-rich proteins that replace histones and bind sperm DNA during spermatogenesis in vertebrates. Previous studies have shown that protamine exons evolve faster than does the protamine intron. It has been suggested that this is a result of a relaxation of functional constraint. However, a more likely explanation is that the evolutionary rate of exons has been accelerated by positive Darwinian...

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Identifiers

PMID: 10335662
DOI: 10.1093/oxfordjournals.molbev.a026153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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