Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The molecular evolution of acrosin in placental mammals

4 Feb 2008

Abstract excerpt

Acrosin is thought to fulfill several different roles in fertilization including that of a serine protease and in secondary zona pellucida (ZP) binding. However, acrosin's importance as a fertilization protein has been questioned. Especially since it was discovered that acrosin knockout mice are fertile. In this study, we explored the sites involved in serine protease activity and secondary binding. We also...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Behavior and Reproduction
Share to Hormonal and reproductive studies
Share to Neuroendocrine regulation and behavior

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18247330
DOI: 10.1002/mrd.20868

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The molecular evolution of acrosin in placental mammalsPMID 18247330Read ↗

Molecular Population Genetics of the Gene Encoding the Human Fertilization Protein Zonadhesin Reveals Rapid Adaptive EvolutionSemantic proximity Read ↗

Positive Selection at Reproductive ADAM Genes with Potential Intercellular Binding ActivitySemantic proximity Read ↗

Adaptive evolution of fertilization proteins within a genus: variation in ZP2 and ZP3 in deer mice (Peromyscus).Semantic proximity Read ↗

Acrosin, the peculiar sperm-specific serine proteaseSemantic proximity Read ↗

Widespread Presence of Human BOULE Homologs among Animals and Conservation of Their Ancient Reproductive FunctionSemantic proximity Read ↗

Pervasive Adaptive Evolution in Primate Seminal ProteinsSemantic proximity Read ↗

Long-term evolution and functional diversification in the members of the nucleophosmin/nucleoplasmin family of nuclear chaperones.Semantic proximity Read ↗

Comparative sequence analyses reveal rapid and divergent evolutionary changes of the WFDC locus in the primate lineage.Semantic proximity Read ↗

Bi-allelic variants inASTLcause abnormal fertilization or oocyte maturation defectsSemantic proximity Read ↗

Variation and Selection in the Putative Sperm-Binding Region of ZP3 in Muroid Rodents: A Comparison between Cricetids and Murines.Semantic proximity Read ↗

Evidence of amino acid diversity-enhancing selection within humans and among primates at the candidate sperm-receptor gene PKDREJ.Semantic proximity Read ↗

Identification of a positively evolving putative binding region with increased variability in posttranslational motifs in zonadhesin MAM domain 2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.