Article
A susceptibility locus for human systemic lupus erythematosus (hSLE1) on chromosome 2q.
Journal of autoimmunity - 1 Mar 2000
Lindqvist A K, Steinsson K, Johanneson B, Kristjánsdóttir H, Arnasson A, Gröndal G, Jonasson I, Magnusson V, Sturfelt G, Truedsson L, Svenungsson E, Lundberg I, Terwilliger J D, Gyllensten U B, Alarcón-Riquelme M E
Abstract excerpt
To identify chromosomal regions containing susceptibility loci for systemic lupus erythematosus (SLE), we performed genome scans in families with multiple SLE patients from Iceland, a geographical and genetic isolate, and from Sweden. A number of chromosomal regions showed maximum lod scores (Z) indicating possible linkage to SLE in both the Icelandic and Swedish families. In the Icelandic families, five regions...
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