Article
Fine mapping of the SLEB2 locus involved in susceptibility to systemic lupus erythematosus.
Genomics - 15 Dec 2000
Magnusson V, Lindqvist A K, Castillejo-López C, Kristjánsdottir H, Steinsson K, Gröndal G, Sturfelt G, Truedsson L, Svenungsson E, Lundberg I, Gunnarsson I, Bolstad A I, Haga H J, Jonsson R, Klareskog L, Alcocer-Varela J, Alarcón-Segovia D, Terwilliger J D, Gyllensten U B, Alarcón-Riquelme M E
Abstract excerpt
We have previously reported linkage of systemic lupus erythematosus to chromosome 2q37 in multicase families from Iceland and Sweden. This locus (SLEB2) was identified by linkage to the markers D2S125 and D2S140. In the present study we have analyzed additional microsatellite markers and SNPs covering a region of 30 cM around D2S125 in an extended set of Nordic families (Icelandic, Swedish, and Norwegian)....
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