Article
The complex immunogenetic basis of systemic lupus erythematosus.
Autoimmunity reviews - 1 May 2008
Castro Jesús, Balada Eva, Ordi-Ros Josep, Vilardell-Tarrés Miquel
Abstract excerpt
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease of unknown etiology with a complex genetic basis that includes many susceptibility genes on multiple chromosomes. As complex human diseases like SLE involve multiple, interacting genetic and environmental determinants, identifying genes for complex traits is challenging and has had limited success so far. Several key approaches that are necessary...
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