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A Role for Centrin 3 in Centrosome Reproduction

7 Feb 2000

Abstract excerpt

Centrosome reproduction by duplication is essential for the bipolarity of cell division, but the molecular basis of this process is still unknown. Mutations in Saccharomyces cerevisiae CDC31 gene prevent the duplication of the spindle pole body (SPB). The product of this gene belongs to the calmodulin super-family and is concentrated at the half bridge of the SPB. We present a functional analysis of HsCEN3, a...

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PMID: 10662768
DOI: 10.1083/jcb.148.3.405

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