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Article

Association of the C-514T polymorphism in the hepatic lipase gene with variations in lipoprotein subclass profiles: The Framingham Offspring Study.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2000

Couture P, Otvos J D, Cupples L A, Lahoz C, Wilson P W, Schaefer E J, Ordovas J M

Abstract excerpt

Hepatic lipase is involved in the metabolism of several lipoproteins and has a key role in reverse cholesterol transport. A common C-to-T substitution at position -514 of the hepatic lipase promoter has been associated with variations in plasma high density lipoprotein cholesterol (HDL-C) levels and hepatic lipase activity. The aim of the current study was to investigate the association of this polymorphism to...

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Source

Identifiers

PMID: 10712408
DOI: 10.1161/01.atv.20.3.815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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