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Article

Microsomal triglyceride transfer protein 493-T variant is associated with resistin levels and C-reactive protein.

Clinical biochemistry - 1 Nov 2007

Gambino Roberto, Bo Simona, Musso Giovanni, Uberti Barbara, Alemanno Natalina, Ghione Federica, Guidi Sabrina, Tiozzo Elisa, Chiusano Valentina, Gentile Luigi, Durazzo Marilena, Pagano Gianfranco, Cassader Maurizio

Abstract excerpt

BACKGROUND: The microsomal triglyceride transfer protein (MTP) is a heterodimeric lipid transfer protein that consists of a large unique 97-kDA subunit and protein disulfide isomerase. MTP is involved in the assembly of apoB-containing lipoprotein and enables the secretion of VLDLs by the liver and chylomicrons by the intestine. The MTP gene is highly polymorphic. The less common T variant has been associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17825806
DOI: 10.1016/j.clinbiochem.2007.07.005

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Microsomal triglyceride transfer protein 493-T variant is associated with resistin levels and C-reactive protein.PMID 17825806Read ↗

Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index.Semantic proximity Read ↗

The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease.Semantic proximity Read ↗

MTP -493G>T polymorphism and susceptibility to nonalcoholic fatty liver disease: a meta-analysis.Semantic proximity Read ↗

A functional polymorphism in the promoter region of the microsomal triglyceride transfer protein (MTP -493G/T) influences lipoprotein phenotype in familial hypercholesterolemia.Semantic proximity Read ↗

Microsomal triglyceride transfer protein gene polymorphism strongly influences circulating malondialdehyde-modified low-density lipoprotein.Semantic proximity Read ↗

The MTP -493TT genotype is associated with peripheral arterial disease: results from the Linz Peripheral Arterial Disease (LIPAD) Study.Semantic proximity Read ↗

Correlation between MTP -493G>T polymorphism and non-alcoholic fatty liver disease risk: a meta-analysis.Semantic proximity Read ↗

Genetic variation in the microsomal triglyceride transfer protein (-493G/T) is associated with hepatic steatosis in patients infected with hepatitis C virus.Semantic proximity Read ↗

Microsomal triglyceride transfer protein (MTP) -493G/T gene polymorphism contributes to fat liver accumulation in HCV genotype 3 infected patients.Semantic proximity Read ↗

Molecular screening of the microsomal triglyceride transfer protein: association between polymorphisms and both abdominal obesity and plasma apolipoprotein B concentration.Semantic proximity Read ↗

Functional analysis of promoter variants in the microsomal triglyceride transfer protein (MTTP) gene.Semantic proximity Read ↗

A common functional exon polymorphism in the microsomal triglyceride transfer protein gene is associated with type 2 diabetes, impaired glucose metabolism and insulin levels.Semantic proximity Read ↗

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