Article
The MTP -493TT genotype is associated with peripheral arterial disease: results from the Linz Peripheral Arterial Disease (LIPAD) Study.
Clinical biochemistry - 1 Jun 2008
Schgoer Wilfried, Eller Philipp, Mueller Thomas, Tancevski Ivan, Wehinger Andreas, Ulmer Hanno, Sandhofer Anton, Ritsch Andreas, Haltmayer Meinhard, Patsch Josef R
Abstract excerpt
OBJECTIVES: Microsomal triglyceride transfer protein (MTP) transfers lipids into apoprotein B-containing lipoproteins for secretion from liver, intestine, and heart. We hypothesized the -493T single nucleotide polymorphism in the MTP promoter region to be associated with altered lipoprotein levels and with presence of peripheral arterial disease (PAD). DESIGN AND METHODS: 433 patients with symptomatic PAD and 433...
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