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Article

Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index.

Journal of lipid research - 1 Jan 2002

Ledmyr Helena, Karpe Fredrik, Lundahl Björn, McKinnon Margaret, Skoglund-Andersson Camilla, Ehrenborg Ewa

Abstract excerpt

The microsomal triglyceride transfer protein (MTP) is required for the assembly and secretion of apolipoprotein B (apoB)-containing lipoproteins from liver and intestine. We set out to study the phenotypic modulation of all common genetic variants in the MTP gene. In addition, we aimed at characterizing the association between the various polymorphisms. A total of 564 healthy men were genotyped for the MTP -493...

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Identifiers

PMID: 11792722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index.PMID 11792722Read ↗

The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease.Semantic proximity Read ↗

Functional analysis of promoter variants in the microsomal triglyceride transfer protein (MTTP) gene.Semantic proximity Read ↗

A functional polymorphism in the promoter region of the microsomal triglyceride transfer protein (MTP -493G/T) influences lipoprotein phenotype in familial hypercholesterolemia.Semantic proximity Read ↗

Effect of microsomal triglyceride transfer protein gene variants (-493G > T, Q95H and H297Q) on plasma lipid levels in healthy middle-aged UK men.Semantic proximity Read ↗

Postprandial plasma ApoB-48 levels are influenced by a polymorphism in the promoter of the microsomal triglyceride transfer protein gene.Semantic proximity Read ↗

A common functional exon polymorphism in the microsomal triglyceride transfer protein gene is associated with type 2 diabetes, impaired glucose metabolism and insulin levels.Semantic proximity Read ↗

The MTP -493TT genotype is associated with peripheral arterial disease: results from the Linz Peripheral Arterial Disease (LIPAD) Study.Semantic proximity Read ↗

Microsomal triglyceride transfer protein gene polymorphism strongly influences circulating malondialdehyde-modified low-density lipoprotein.Semantic proximity Read ↗

Influence of microsomal triglyceride transfer protein promoter polymorphism -493 GT on fasting plasma triglyceride values and interaction with treatment response to atorvastatin in subjects with heterozygous familial hypercholesterolaemia.Semantic proximity Read ↗

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Common polymorphism in promoter of microsomal triglyceride transfer protein gene influences cholesterol, ApoB, and triglyceride levels in young african american men: results from the coronary artery risk development in young adults (CARDIA) study.Semantic proximity Read ↗

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