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Article

A mutant streptokinase lacking the C-terminal 42 amino acids is less immunogenic.

Immunology letters - 1 Dec 1999

Torrèns I, Ojalvo A G, Seralena A, Hayes O, de la Fuente J

Abstract excerpt

Streptokinase (SK) is the most widely used compound for the treatment of myocardial infarction and the least expensive thrombolytic agent, but a drawback to its use is the widespread presence of anti-SK antibodies (Abs). Clinical failure of the activation of the fibrinolytic system by SK has been reported due to the presence of a high titer of anti-SK neutralizing Abs. Patients receiving SK therapy develop high...

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Source

Identifiers

PMID: 10656677
DOI: 10.1016/s0165-2478(99)00151-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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