Article
[Staphylokinase and its mutants: a new generation of thrombolytic agents].
Journal des maladies vasculaires - 1 Apr 1998
Lebrazi J, Elalamy I, Helft G, Samama M M
Abstract excerpt
Staphylokinase which is extracted from Staphylococci has been known for more than 40 years as a profibrinolytic compound. It has been obtained more recently by genetic engineering. Staphylokinase activates plasminogen into plasmin. It is a promising new thrombolytic agent for the treatment of acu...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Fibrinolytic Agents
- Humans
- Metalloendopeptidases
- Molecular Sequence Data
- Mutation
- Protein Engineering
- Pulmonary Embolism