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Article

Preparation of a novel streptokinase mutant with improved stability.

Thrombosis and haemostasis - 1 May 1998

Shi G Y, Chang B I, Su S W, Young K C, Wu D H, Chang L C, Tsai Y S, Wu H L

Abstract excerpt

The novel mutant streptokinase, SK-K59E, can activate human plasminogen as efficiently as the purified commercially available streptokinase. Several peptide bonds including Lys59-Ser60 in native streptokinase were hydrolyzed in reaction with plasmin and peptides of small molecular masses were generated. The plasminogen activator activity of native streptokinase in reaction with human plasmin declined to 25% of...

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PMID: 9609235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Preparation of a novel streptokinase mutant with improved stability.PMID 9609235Read ↗

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