Article
Tyrosine phosphorylation of the <i>Helicobacter pylori</i> CagA antigen after <i>cag</i> -driven host cell translocation
1 Feb 2000
Abstract excerpt
Helicobacter pylori strains associated with severe tissue damage and inflammation possess a unique genetic locus, cag, containing 31 genes originating from a distant event of horizontal transfer and retained as a pathogenicity island. The cag system is an Helicobacter-specific type IV secretion engine involved in cellular responses like induction of pedestals, secretion of IL-8, and phosphorylation of proteic...
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