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Article

Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation.

Genes & development - 15 Jan 2000

Kieslinger M, Woldman I, Moriggl R, Hofmann J, Marine J C, Ihle J N, Beug H, Decker T

Abstract excerpt

Stat5 is activated by multiple receptors of hematopoietic cytokines. To study its role during hematopoiesis, we have generated primary chicken myeloblasts expressing different dominant-negative (dn) alleles of Stat5. This caused a striking inability to generate mature cells, due to massive apopto...

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Identifiers

PMID: 10652277
PMCID: PMC316353

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10652277-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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