Article
Genes for epilepsy mapped in the mouse.
Science (New York, N.Y.) - 9 Aug 1991
Rise M L, Frankel W N, Coffin J M, Seyfried T N
Abstract excerpt
The neurological mutant mouse strain E1 is a model for complex partial seizures in humans. The inheritance of epileptic seizures with seven conventional chromosomal markers and over 60 endogenous proviral markers was studied by means of back-crosses of E1 with two seizure-resistant strains, DBA/2...
Topics
- Animals
- Chromosome Mapping
- Crosses, Genetic
- Epilepsy
- Female
- Genetic Predisposition to Disease
- Male
- Mice
- Mice, Inbred Strains
- Mice, Neurologic Mutants
- Recombination, Genetic
- Seizures
- Software