Article
Chromosomal mapping of genes for epilepsy in NER: a rat strain with tonic-clonic seizures.
Epilepsia - 1 Aug 2000
Maihara T, Noda A, Yamazoe H, Voigt B, Kitada K, Serikawa T
Abstract excerpt
PURPOSE: NER is a mutant rat strain that exhibits spontaneous tonic-clonic convulsions accompanied by epileptic discharges on ictal EEG and serves as a model for generalized tonic-clonic seizures in humans. Our previous experiments have suggested that a major autosomal recessive gene and several minor genes regulate the inheritance of tonic-clonic seizures in NER. The purpose of this study was to confirm the mode...
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