Article
Interaction of PKN with a neuron-specific basic helix-loop-helix transcription factor, NDRF/NeuroD2.
Brain research. Molecular brain research - 10 Dec 1999
Shibata H, Oda H, Mukai H, Oishi K, Misaki K, Ohkubo H, Ono Y
Abstract excerpt
By the yeast two-hybrid screening of a human brain cDNA library with the amino-terminal regulatory region of PKN as a bait, a clone encoding a neuron-specific basic Helix-Loop-Helix (bHLH) transcription factor, NDRF/NeuroD2 was isolated. NDRF/NeuroD2 was co-precipitated with PKN from the lysate of COS-7 cells transfected with both expression constructs for NDRF/NeuroD2 and PKN. In vitro binding studies using the...
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