Article
Pkn is a novel partner of cyclin T2a in muscle differentiation.
Journal of cellular physiology - 1 Apr 2006
Cottone Giuliano, Baldi Alfonso, Palescandolo Emanuele, Manente Lucrezia, Penta Roberta, Paggi Marco G, De Luca Antonio
Abstract excerpt
With the aim to find novel partners of human Cyclin T2a, we performed a two-hybrid screening in yeast using the full-length cDNA of this cyclin as bait, and a human heart cDNA library as preys source. Upon several interesting genes selected, our attention has been focused on the cDNA coding for PKNalpha, a fatty acid- and Rho-activated serine/threonine protein kinase, having a catalytic domain homologous to...
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