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Article

Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1.

Molecular and cellular biology - 1 Jan 2003

Ray Subir K, Nishitani Junko, Petry Mary W, Fessing Michael Y, Leiter Andrew B

Abstract excerpt

The basic helix-loop-helix protein BETA2/NeuroD activates transcription of the secretin gene and is essential for terminal differentiation of secretin-producing enteroendocrine cells. However, in heterodimeric complexes with its partner basic helix-loop-helix proteins, BETA2 does not appear to be a strong activator of transcription by itself. Mutational analysis of a proximal enhancer in the secretin gene...

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Identifiers

PMID: 12482979
DOI: 10.1128/MCB.23.1.259-271.2003
PMCID: PMC140679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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