Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paraoxonase 1 status as a risk factor for disease or exposure.

Advances in experimental medicine and biology - 1 Jan 2010

Richter Rebecca J, Jarvik Gail P, Furlong Clement E

Abstract excerpt

Human paraoxonase 1 (PON1) has broad substrate specificity and has been shown to protect against exposure to some organophosphorus (OP) insecticides due to its ability to hydrolyze toxic metabolites of some organophosphorothioate insecticides. PON1 status has been shown to be important in protecting against vascular disease, presumably due to the not-as-yet fully characterized role of the three PON proteins in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryldialkylphosphatase
Share to Carotid Artery Diseases
Share to Hydrolysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Insecticides

Share to Lactones

Share to Organophosphorus Compounds

Share to Pseudomonas

Share to Quorum Sensing

Source

Open in PubMed Open full text

Identifiers

PMID: 20221868
DOI: 10.1007/978-1-60761-350-3_4
PMCID: PMC2868909

Genes

PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paraoxonase 1 status as a risk factor for disease or exposure.PMID 20221868Read ↗

Paraoxonase (PON1): from toxicology to cardiovascular medicine.Semantic proximity Read ↗

Paraoxonase-1 (PON1) Status Analysis Using Non-Organophosphate Substrates.Semantic proximity Read ↗

Paraoxonases-1, -2 and -3: What are their functions?Semantic proximity Read ↗

Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity.Semantic proximity Read ↗

Pharmacogenetics of paraoxonases: a brief review.Semantic proximity Read ↗

Determination of paraoxonase 1 status and genotypes at specific polymorphic sites.Semantic proximity Read ↗

Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism.Semantic proximity Read ↗

Bayesian meta-analysis of inter-phenotypic differences in human serum paraoxonase-1 activity for chemical risk assessment.Semantic proximity Read ↗

Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1.Semantic proximity Read ↗

Paraoxonase (PON1) polymorphism and activity as the determinants of sensitivity to organophosphates in human subjects.Semantic proximity Read ↗

Determination of paraoxonase (PON1) status requires more than genotyping.Semantic proximity Read ↗

Paraoxonase 1 polymorphisms within a Mississippi USA population as possible biomarkers of enzyme activities associated with disease susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.