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Article

Early androgen treatment decreases cognitive function and catecholamine innervation in an animal model of ADHD.

Behavioural brain research - 1 Jan 2000

King J A, Barkley R A, Delville Y, Ferris C F

Abstract excerpt

The spontaneously hypertensive rat (SHR) has been used as an animal model of attention deficit hyperactivity disorder (ADHD). The present study was designed to determine whether exposure to elevated androgen levels early in development demonstrated impairments in cognitive functioning, neuroendocrine control, and brain development parallel to those seen in ADHD children. The animals (SHR and Wistar (WKY)...

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PMID: 10628728
DOI: 10.1016/s0166-4328(99)00113-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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