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Article

Genetically determined differences in noradrenergic function: The spontaneously hypertensive rat model.

Brain research - 15 Jun 2016

Sterley Toni-Lee, Howells Fleur M, Russell Vivienne A

Abstract excerpt

While genetic predisposition is a major factor, it is not known how development of attention-deficit/hyperactivity disorder (ADHD) is modulated by early life stress. The spontaneously hypertensive rat (SHR) displays the behavioral characteristics of ADHD (poorly sustained attention, impulsivity, hyperactivity) and is the most widely studied genetic model of ADHD. We have previously shown that SHR have...

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PMID: 26612520
DOI: 10.1016/j.brainres.2015.11.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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