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Article

Positive effects of early androgen therapy on the behavioral phenotype of boys with 47,XXY.

American journal of medical genetics. Part C, Seminars in medical genetics - 1 Jun 2015

Samango-Sprouse Carole, Stapleton Emily J, Lawson Patrick, Mitchell Francie, Sadeghin Teresa, Powell Sherida, Gropman Andrea L

Abstract excerpt

47, XXY occurs in up to 1 in 650 male births and is associated with androgen deficiency, neurodevelopmental delays, and atypical social-behaviors. Previously, we showed that young boys with 47, XXY who received early hormonal therapy (EHT) had significantly improved neurodevelopment. The objective of this follow-up study was to examine the effects of EHT on social behavior in boys with 47, XXY. The study...

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Identifiers

PMID: 25939399
DOI: 10.1002/ajmg.c.31437

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