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Article

Preconception paternal morphine exposure leads to an impulsive phenotype in male rat progeny.

Psychopharmacology - 1 Dec 2021

Azadi Maryam, Moazen Parisa, Wiskerke Joost, Semnanian Saeed, Azizi Hossein

Abstract excerpt

RATIONALE: Identifying the long-term neurocognitive implications of opioid addiction may further our understanding of the compulsive nature of this brain disorder. The aim of this study was to examine the effects of paternal adolescent opiate exposure on cognitive performance (visual attention, impulsivity, and compulsivity) in the next generation. METHODS: Male Wistar rats received escalating doses of morphine...

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PMID: 34427719
DOI: 10.1007/s00213-021-05962-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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