Article
High novelty-seeking predicts aggression and gene expression differences within defined serotonergic cell groups.
Brain research - 24 Oct 2011
Kerman Ilan A, Clinton Sarah M, Bedrosian Tracy A, Abraham Antony D, Rosenthal Devin T, Akil Huda, Watson Stanley J
Abstract excerpt
Aggression frequently coincides with specific dimensions of emotionality, such as impulsivity, risk-taking, and drug abuse. Serotonergic (5-HTergic) neurotransmission contributes to the regulation of numerous neurobiological functions, and is thought to play a key role in modulating aggressive responses. The current study uses selectively-bred High (bHR) and Low (bLR) Responder rats that exhibit differences in...
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