Early stress and genetic influences on hypothalamic-pituitary-adrenal axis functioning in adulthood.

doi:10.1006/hbeh.1999.1525

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Article

Early stress and genetic influences on hypothalamic-pituitary-adrenal axis functioning in adulthood.

Hormones and behavior - 1 Oct 1999

King J A, Edwards E

Abstract excerpt

During early development, environmental challenges set the stage for permanent changes in the functioning of the pituitary-adrenal stress response. Since these data have been reported almost exclusively in single rat strains the role of phenotypic and genotypic factors in shaping the stress response is relatively unknown. This study examined whether the phenotypic/genetic profile of the rat influences the...

Topics

Adrenocorticotropic Hormone
Animals
Cold Temperature
Corticosterone
Electroshock
Female
Genotype
Helplessness, Learned
Hypothalamo-Hypophyseal System
Maternal Deprivation
Pituitary-Adrenal System
Pregnancy
Rats
Rats, Inbred Strains
Rats, Sprague-Dawley
Species Specificity
Stress, Psychological

Source

Open in PubMed

Identifiers

PMID: 10506532
DOI: 10.1006/hbeh.1999.1525

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