Article
Base-pairing between 23S rRNA and tRNA in the ribosomal A site.
Molecular cell - 1 Nov 1999
Kim D F, Green R
Abstract excerpt
The aminoacyl (A site) tRNA analog 4-thio-dT-p-C-p-puromycin (s4TCPm) photochemically cross-links with high efficiency and specificity to G2553 of 23S rRNA and is peptidyl transferase reactive in its cross-linked state, establishing proximity between the highly conserved 2555 loop in domain V of 23S rRNA and the universally conserved CCA end of tRNA. To test for base-pairing interactions between 23S rRNA and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
