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Article

Rapid exchange of A:T base pairs is essential for recognition of DNA homology by human Rad51 recombination protein.

Molecular cell - 1 Nov 1999

Gupta R C, Folta-Stogniew E, O'Malley S, Takahashi M, Radding C M

Abstract excerpt

Human Rad51 belongs to a ubiquitous family of proteins that enable a single strand to recognize homology in duplex DNA, and thereby to initiate genetic exchanges and DNA repair, but the mechanism of recognition remains unknown. Kinetic analysis by fluorescence resonance energy transfer combined with the study of base substitutions and base mismatches reveals that recognition of homology, helix destabilization,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10619018
DOI: 10.1016/s1097-2765(00)80381-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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