Article
Effect of dynamic compressive loading and its combination with a growth factor on the chondrocytic phenotype of 3-dimensional scaffold-embedded chondrocytes.
Acta orthopaedica - 1 Dec 2009
Ando Kosei, Imai Shinji, Isoya Eiji, Kubo Mitsuhiko, Mimura Tomohiro, Shioji Suguru, Ueyama Hisao, Matsusue Yoshitaka
Abstract excerpt
BACKGROUND AND PURPOSE: Three-dimensionally (3D-) embedded chondrocytes have been suggested to maintain the chondrocytic phenotype. Furthermore, mechanical stress and growth factors have been found to be capable of enhancing cell proliferation and ECM synthesis. We investigated the effect of mech...
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