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Article

Osteocyte differentiation and the formation of an interconnected cellular network in vitro.

European cells & materials - 24 May 2016

Mc Garrigle M J, Mullen C A, Haugh M G, Voisin M C, McNamara L M

Abstract excerpt

Extracellular matrix (ECM) stiffness and cell density can regulate osteoblast differentiation in two dimensional environments. However, it is not yet known how osteoblast-osteocyte differentiation is regulated within a 3D ECM environment, akin to that existing in vivo. In this study we test the hypothesis that osteocyte differentiation is regulated by a 3D cell environment, ECM stiffness and cell density. We...

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Source

Identifiers

PMID: 27215740
DOI: 10.22203/ecm.v031a21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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