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Article

Influence of topography of nanofibrils of three-dimensional collagen gel beads on the phenotype, proliferation, and maturation of osteoblasts.

Journal of biomedical materials research. Part A - 15 Dec 2009

Tsai Shiao-Wen, Chen Chia-Chun, Chen Pao-Liang, Hsu Fu-Yin

Abstract excerpt

Our objectives were to fabricate three-dimensional collagen/chondroitin sulfate beads using mild conditions and no chemical reagents, and subsequently to investigate the influence of the nanotopography of these beads on primary osteoblast and MG63 cell responses, including cell morphology, proliferation rate, and gene expression. The major principle used to prepare beads was complex coacervation, with which we...

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PMID: 19097153
DOI: 10.1002/jbm.a.32324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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