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Article

Applying an excessive mechanical stress alters the effect of subchondral osteoblasts on chondrocytes in a co-culture system.

European journal of oral sciences - 1 Apr 2010

Lin Yu-Yu, Tanaka Nobuaki, Ohkuma Satoru, Iwabuchi Yasunori, Tanne Yuki, Kamiya Takashi, Kunimatsu Ryo, Huang Yu-Ching, Yoshioka Motoko, Mitsuyoshi Tomomi, Tanimoto Kotaro, Tanaka Eiji, Tanne Kazuo

Abstract excerpt

Osteoarthritis (OA) sometimes occurs as a consequence of repeated microtrauma involved in parafunction, which may lead to microfracture in the subchondral bone. The aim of this in vitro study was to evaluate the effects of subchondral osteoblasts in loading with repeated excessive mechanical stre...

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PMID: 20487004
DOI: 10.1111/j.1600-0722.2010.00710.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20487004-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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