Mechanical stress induced cellular orientation and phenotypic modulation of 3-D cultured smooth muscle cells.

Article

Mechanical stress induced cellular orientation and phenotypic modulation of 3-D cultured smooth muscle cells.

ASAIO journal (American Society for Artificial Internal Organs : 1992) - 1 Jan 2000

Kanda K, Matsuda T, Oka T

Abstract excerpt

The effect of periodic stretch on cellular orientation and intracellular ultrastructure of three-dimensionally (3-D) cultured arterial smooth muscle cells (SMCs) was investigated. Ring shaped hybrid tissues were prepared by thermal gelation of a mixed solution of Type I collagen and SMCs derived...

Topics

Animals
Cattle
Cell Differentiation
Collagen
Diffusion Chambers, Culture
Extracellular Matrix
Isometric Contraction
Microscopy, Electron
Muscle, Smooth, Vascular
Phenotype
Pulsatile Flow

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