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Article

Mechanical stress induced cellular orientation and phenotypic modulation of 3-D cultured smooth muscle cells.

ASAIO journal (American Society for Artificial Internal Organs : 1992) - 1 Jan 2000

Kanda K, Matsuda T, Oka T

Abstract excerpt

The effect of periodic stretch on cellular orientation and intracellular ultrastructure of three-dimensionally (3-D) cultured arterial smooth muscle cells (SMCs) was investigated. Ring shaped hybrid tissues were prepared by thermal gelation of a mixed solution of Type I collagen and SMCs derived from bovine aorta. The gels were subjected to three modes of stress loading: floated (control), stretched isometrically...

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PMID: 8268625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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