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Article

High activity of the calcineurin A subunit with a V314 deletion.

Biological chemistry - 1 Nov 1999

Yan L, Wei Q

Abstract excerpt

A deletion mutant (V314) of the calcineurin A subunit was constructed using site-directed mutagenesis. Its phosphatase activity and function were then characterized. The V314 deletion significantly altered the phosphatase activity, which was more than ten times higher than that of wild-type calcineurin, the calcineurin-immunosuppressant/immunophilin interaction, the effect of metal ions and calcineurin subunit...

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Identifiers

PMID: 10614820
DOI: 10.1515/BC.1999.163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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