Article
Regulation and temporal expression patterns of Vibrio cholerae virulence genes during infection.
Cell - 10 Dec 1999
Lee S H, Hava D L, Waldor M K, Camilli A
Abstract excerpt
The temporal expression patterns of the critical Vibrio cholerae virulence genes, tcpA and ctxA, were determined during infection using a recombinase reporter. TcpA was induced biphasically in two temporally and spatially separable events in the small intestine, whereas ctxA was induced monophasically only after, and remarkably, dependent upon, tcpA expression; however, this dependence was not observed during in...
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