Article
Upregulation of virulence genes promotes Vibrio cholerae biofilm hyperinfectivity.
Proceedings of the National Academy of Sciences of the United States of America - 19 May 2020
Gallego-Hernandez A L, DePas W H, Park J H, Teschler J K, Hartmann R, Jeckel H, Drescher K, Beyhan S, Newman D K, Yildiz F H
Abstract excerpt
Vibrio cholerae remains a major global health threat, disproportionately impacting parts of the world without adequate infrastructure and sanitation resources. In aquatic environments, V. cholerae exists both as planktonic cells and as biofilms, which are held together by an extracellular matrix. V. cholerae biofilms have been shown to be hyperinfective, but the mechanism of hyperinfectivity is unclear. Here we...
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