Mutation in the relA gene of Vibrio cholerae affects in vitro and in vivo expression of virulence factors.

Abstract excerpt

The relA gene product determines the level of (p)ppGpp, the effector nucleotides of the bacterial stringent response that are also involved in the regulation of other functions, like antibiotic production and quorum sensing. In order to explore the possible involvement of relA in the regulation of virulence of Vibrio cholerae, a relA homolog from the organism (relA(VCH)) was cloned and sequenced. The relA(VCH)...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cholera
• Share to Cholera Toxin
• Share to Ileum