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Expression of Cholera Toxin (CT) and the Toxin Co-Regulated Pilus (TCP) by Variants of ToxT in Vibrio cholerae Strains.

Toxins - 17 Aug 2023

Lee Donghyun, Choi Hunseok, Son Seonghyeon, Bae Jonghyun, Joo Jayun, Kim Dong Wook, Kim Eun Jin

Abstract excerpt

The expression of the two major virulence genes of Vibrio cholerae-tcpA (the major subunit of the toxin co-regulated pilus) and ctxAB (cholera toxin)-is regulated by the ToxR regulon, which is triggered by environmental stimuli during infection within the human small intestine. Special culture methods are required to induce the expression of virulence genes in V. cholerae in the laboratory setting. In the present...

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Identifiers

PMID: 37624264
DOI: 10.3390/toxins15080507
PMCID: PMC10467113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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