Article
Vibrio vulnificus rtxE is important for virulence, and its expression is induced by exposure to host cells.
Infection and immunity - 1 Apr 2008
Lee Byung Cheol, Lee Jeong Hyun, Kim Myung Won, Kim Byoung Sik, Oh Man Hwan, Kim Kun-Soo, Kim Tae Sung, Choi Sang Ho
Abstract excerpt
Numerous secreted virulence factors have been proposed to account for the fulminating and destructive nature of Vibrio vulnificus infections. A mutant of V. vulnificus that exhibited less cytotoxicity to INT-407 human intestinal epithelial cells was screened from a library of mutants constructed by random transposon mutagenesis. A transposon-tagging method was used to identify and clone an open reading frame...
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