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Article

ToxR regulon of Vibrio cholerae and its expression in vibrios shed by cholera patients.

Proceedings of the National Academy of Sciences of the United States of America - 4 Mar 2003

Bina James, Zhu Jun, Dziejman Michelle, Faruque Shah, Calderwood Stephen, Mekalanos John

Abstract excerpt

Toxigenic Vibrio cholerae cause cholera, a severe diarrheal disease responsible for significant morbidity and mortality worldwide. Two determinants, cholera enterotoxin (CT) and toxin coregulated pilus (TCP) are critical factors responsible for this organism's virulence. The genes for these virulence determinants belong to a network of genes (the ToxR regulon) whose expression is modulated by transcriptional...

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Identifiers

PMID: 12601157
DOI: 10.1073/pnas.2628026100
PMCID: PMC151421

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Source receipt: pubmed, retrieved 7 Sept 2026.

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ToxR regulon of Vibrio cholerae and its expression in vibrios shed by cholera patients.PMID 12601157Read ↗

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