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Article

Fas-deficient lpr mice are more susceptible to graft-versus-host disease.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2000

van Den Brink M R, Moore E, Horndasch K J, Crawford J M, Hoffman J, Murphy G F, Burakoff S J

Abstract excerpt

The Fas/Fas ligand (FasL) pathway is involved in a variety of regulatory mechanisms that could be important for the development of graft-vs-host disease (GVHD) after bone marrow transplantation (BMT), such as cytolysis of target cells by cytotoxic T cells, regulation of inflammatory responses, peripheral deletion of autoimmune cells, costimulation of T cells, and activation-induced cell death. To further evaluate...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10605044
DOI: 10.4049/jimmunol.164.1.469

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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