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Article

ExoT of cytotoxic Pseudomonas aeruginosa prevents uptake by corneal epithelial cells.

Infection and immunity - 1 Jan 2000

Cowell B A, Chen D Y, Frank D W, Vallis A J, Fleiszig S M

Abstract excerpt

The presence of invasion-inhibitory activity that is regulated by the transcriptional activator ExsA of cytotoxic Pseudomonas aeruginosa has previously been proposed. The results of this study show that both ExoT and ExoS, known type III secreted effector proteins of P. aeruginosa that are regulated by ExsA, possess this activity. Invasion was reduced 94.4% by ExoT and 96.0% by ExoS. Invasion-inhibitory activity...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10603417
DOI: 10.1128/IAI.68.1.403-406.2000
PMCID: PMC97150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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